藩 HAN - feudal clan, lord
脈 MYAKU - pulse, vein, blood vessel
器 KI, utsuwa - vessel, container, apparatus
粒 RYUU, tsubu - a grain
壮 SOU - manly, strong
All take 大 (DAI, oo(kii) - big) in front to make a word, but only 大粒 uses the "Oo" reading (Ootsubu); the others are all "Tai/Dai-":
大藩 TAIHAN - a large clan
大脈 DAIMYAKU - Peak pulse
大器 TAIKI - a large container
大粒 ootsubu - a large grain
大壮 TAISOU - large, great